ASIC4 Antibody / ACCN4
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q96FT7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 23-52 from the human protein was used as the immunogen for this ASIC4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ASIC4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ASIC4 antibody is available for research use only.
Storage Conditions
Aliquot the ASIC4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ASIC4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ASIC4 antibody western blot analysis in human HepG2 lysate. Predicted molecular weight ~70 kDa.
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