ADAM17 Antibody
ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Product Specifications
UniProt
P78536
Host
Rabbit
Immunogen
A portion of amino acids 195-224 from the human protein was used as the immunogen for this ADAM17 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ADAM17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ADAM17 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6680035/datasheet/f44300-0.08ml.pdf
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
