Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NANOG Antibody (N-Terminal Region)

NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

Q9H9S0

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 15-49 from the human protein was used as the immunogen for this NANOG antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF, IHC, FACS, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NANOG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NANOG antibody is available for research use only.

Storage Conditions

Aliquot the NANOG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NANOG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Primate

Image Legend

Western blot analysis of NANOG antibody and K562 lysate; Predicted molecular weight: 35-45 kDa.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Cerubidine 10mg
A10194-10 10 mg

Cerubidine 10mg

Ask
View Details
Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)
MBS1317411-01 0.02 mg (E-Coli)

Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)

Ask
View Details
Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)
MBS1317411-02 0.02 mg (Yeast)

Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)

Ask
View Details
Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)
MBS1317411-03 0.1 mg (E-Coli)

Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)

Ask
View Details
Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)
MBS1317411-04 0.1 mg (Yeast)

Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)

Ask
View Details
Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)
MBS1317411-05 0.02 mg (Baculovirus)

Recombinant Bacillus anthracis 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (fabH2)

Ask
View Details