Fyn Antibody
Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P39688
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 507-535 from the mouse protein was used as the immunogen for this Fyn antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Fyn antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Fyn antibody is available for research use only.
Storage Conditions
Aliquot the Fyn antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Fyn antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Human, Pig, Rat
Image Legend
Fyn antibody western blot analysis in mouse lung tissue lysate. Predicted molecular weight: ~59 kDa.
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