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PCSK6 Antibody / PACE4

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P29122

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 659-688 from the human protein was used as the immunogen for this PCSK6 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the PCSK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PCSK6 antibody is available for research use only.

Storage Conditions

Aliquot the PCSK6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PCSK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

PCSK6 antibody western blot analysis in K562 lysate.

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