A2M Antibody / Alpha-2-macroglobulin
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P01023
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1162-1192 from the human protein was used as the immunogen for this A2M antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the A2M antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This A2M antibody is available for research use only.
Storage Conditions
Aliquot the A2M antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the A2M antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
A2M antibody western blot analysis in human placenta tissue lysate. Predicted molecular weight: ~163/200kDa (unmodified/glycosylated) .
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