RUNX3 Antibody
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
Q13761
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, IF, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RUNX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RUNX3 antibody is available for research use only.
Storage Conditions
Aliquot the RUNX3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the RUNX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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