NEDD9 Antibody / hEF1 / CAS-L
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B-and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q14511
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 335-363 from the human protein was used as the immunogen for this NEDD9 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the NEDD9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NEDD9 antibody is available for research use only.
Storage Conditions
Aliquot the NEDD9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NEDD9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
NEDD9 antibody western blot analysis in MCF-7 lysate. Predicted molecular weight: ~93kDa.
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