HMGB1 Antibody
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V (D) J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) . Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P09429
Host
Rabbit
Reactivity
Human
Immunogen
This HMGB1 antibody was produced from rabbits immunized with human HMGB1 recombinant protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the HMGB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HMGB1 antibody is available for research use only.
Storage Conditions
Aliquot the HMGB1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HMGB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Image Legend
HMGB1 antibody western blot analysis in CEM lysate. Predicted molecular weight ~25 kDa.
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