Irak1 Antibody
Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
Q62406
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 405-433 from the mouse protein was used as the immunogen for this Irak1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Irak1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Irak1 antibody is available for research use only.
Storage Conditions
Aliquot the Irak1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Irak1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Irak1 antibody western blot analysis in mouse Neuro-2a lysate. Predicted molecular weight ~76 kDa.
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