EDG8 Antibody
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9H228
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 219-247 from the human protein was used as the immunogen for this EDG8 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the EDG8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This EDG8 antibody is available for research use only.
Storage Conditions
Aliquot the EDG8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the EDG8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
EDG8 antibody western blot analysis in A549 lysate. Predicted molecular weight: ~42kDa.
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