IL-33 Antibody

Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O95760

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 50-79 from the human protein was used as the immunogen for this IL-33 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the IL-33 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IL-33 antibody is available for research use only.

Storage Conditions

Aliquot the IL-33 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the IL-33 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of IL-33 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the IL33 gene. Predicted molecular weight: ~31/26kDa (isoforms a/b) .