Rage Antibody
RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9WVS4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Rage antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Rage antibody is available for research use only.
Storage Conditions
Aliquot the Rage antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Rage antibody western blot analysis in NCI-H292 lysate. Predicted molecular weight: 45-55kDa depending on glycosylation level.
Frequently Asked Questions
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