TRPV3 Antibody
TRPV3 is a putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q8K424
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 90-119 from the mouse protein was used as the immunogen for this TRPV3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TRPV3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TRPV3 antibody is available for research use only.
Storage Conditions
Aliquot the TRPV3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TRPV3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of TRPV3 antibody and mouse heart tissue lysate
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