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FOXO3 Antibody

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

O43524

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 224-253 from the human protein was used as the immunogen for this FOXO3 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, IF, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the FOXO3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FOXO3 antibody is available for research use only.

Storage Conditions

Aliquot the FOXO3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the FOXO3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse

Image Legend

FOXO3 antibody western blot analysis in CEM lysate. Expected molecular weight: 71-90 kDa depending on glycosylation level.

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