Irak4 Antibody
Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity) .
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q8R4K2
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Irak4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Irak4 antibody is available for research use only.
Storage Conditions
Aliquot the Irak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Irak4 antibody western blot analysis in MDA-MB435 lysate. Predicted molecular weight 52/37 kDa (isoforms 1/2) .
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