NLRP12 Antibody
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P59046
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 183-212 from the human protein was used as the immunogen for this NLRP12 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the NLRP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NLRP12 antibody is available for research use only.
Storage Conditions
Aliquot the NLRP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
NLRP12 antibody western blot analysis in human placenta tissue lysate. Predicted molecular weight: ~119kDa, routinely observed at 100~119kDa.
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