GSK264220A
GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].
Product Specifications
CAS Number
685506-42-7
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gsk264220a.html
Purity
99.24
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=C(C)OC(S(=O)(N2CCCCC2)=O)=C1)NC3=CC=CC=C3
Molecular Formula
C17H21N3O4S
Molecular Weight
363.43
Precautions
H315, H319
References & Citations
[1]Keller PM, et al. A high-throughput screen for endothelial lipase using HDL as substrate. J Biomol Screen. 2008 Jul;13 (6) :468-75.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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