GSK264220A

GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].

Product Specifications

CAS Number

[685506-42-7]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Lipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gsk264220a.html

Purity

99.24

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(NC1=C(C)OC(S(=O)(N2CCCCC2)=O)=C1)NC3=CC=CC=C3

Molecular Formula

C17H21N3O4S

Molecular Weight

363.43

Precautions

H315, H319

References & Citations

[1]Keller PM, et al. A high-throughput screen for endothelial lipase using HDL as substrate. J Biomol Screen. 2008 Jul;13 (6) :468-75.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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