BMP7 Antibody

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq].

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

P18075

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 280-309 from the human protein was used as the immunogen for this BMP7 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the BMP7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This BMP7 antibody is available for research use only.

Storage Conditions

Aliquot the BMP7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the BMP7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of BMP7 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the BMP7 gene. Predicted molecular weight: 49 kDa protein cleaved into ~33 and ~15 kDa segments.