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NONO Antibody

This gene encodes 'Non POU domain containing octamer binding protein', or NONO, an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq].

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

Q15233

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 45-74 from the human protein was used as the immunogen for this NONO antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NONO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NONO antibody is available for research use only.

Storage Conditions

Aliquot the NONO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NONO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat

Location

Nuclear

Image Legend

NONO antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue

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