LDHA Antibody
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:10-1:50
UniProt
P00338
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 204-232 from the human protein was used as the immunogen for this LDHA antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the LDHA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This LDHA antibody is available for research use only.
Storage Conditions
Aliquot the LDHA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the LDHA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Location
Cytoplasmic, nuclear
Image Legend
LDHA antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~36kDa.
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