NLRP6 Antibody
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD) . NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:4000
UniProt
P59044
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the NLRP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NLRP6 antibody is available for research use only.
Storage Conditions
Aliquot the NLRP6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
NLRP6 antibody western blot analysis in human placenta tissue lysate. Predicted molecular weight ~99 kDa.
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Frequently Asked Questions
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