NLRP10 Antibody
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) . The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q86W26
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the NLRP10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NLRP10 antibody is available for research use only.
Storage Conditions
Aliquot the NLRP10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
NLRP10 antibody western blot analysis in human placenta tissue lysate.
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