AR Antibody
The androgen receptor, also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. It is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the AR is as a DNA-binding transcription factor that regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P10275
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 475-504 from the human protein was used as the immunogen for this AR antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the AR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This AR antibody is available for research use only.
Storage Conditions
Aliquot the AR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
AR antibody western blot analysis in ZR-75-1 lysate
Frequently Asked Questions
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