Bad Antibody
Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
Q92934
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 53-81 from the human protein was used as the immunogen for this Bad antibody.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Bad antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Bad antibody is available for research use only.
Storage Conditions
Aliquot the Bad antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of Bad antibody and HL-60 lysate. Predicted molecular weight: 19-23 kDa.
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