MGMT Antibody
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Product Specifications
UniProt
P16455
Host
Rabbit
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for this MGMT antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, WB, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MGMT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MGMT antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6679532/datasheet/f42543-0.4ml.pdf
CAS Number
9007-83-4
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