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FAP Antibody

Fibroblast activation protein is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q12884

Host

Rabbit

Reactivity

Human

Immunogen

This FAP antibody was produced from rabbits immunized with the protein of human FAP.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Strore at 4oC for up to one month. For long term, aliquot the FAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FAP antibody is available for research use only.

Storage Conditions

Strore at 4°C for up to one month. For long term, aliquot the FAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the FAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

FAP antibody western blot analysis in NCI-H292 lysate. Predicted molecular weight 88~95 kDa (monomer) and 170 kDa (dimer)

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