SDHD Antibody
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
O14521
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 13-42 from the human protein was used as the immunogen for this SDHD antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, IF, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SDHD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SDHD antibody is available for research use only.
Storage Conditions
Aliquot the SDHD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SDHD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
SDHD antibody western blot analysis in HeLa lysate
Frequently Asked Questions
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PLEKHF2, ID (PLEKHF2, ZFYVE18, Pleckstrin homology domain-containing family F member 2, PH and FYVE domain-containing protein 2, Phafin-2, Zinc finger FYVE domain-containing protein 18)
