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MeCP2 Antibody

MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]

Product Specifications

UniProt

P51608

Host

Rabbit

Immunogen

A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MeCP2 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6679382/datasheet/f41828-0.4ml.pdf

CAS Number

9007-83-4

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