MeCP2 Antibody
MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]
Product Specifications
UniProt
P51608
Host
Rabbit
Immunogen
A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MeCP2 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6679381/datasheet/f41828-0.08ml.pdf
CAS Number
9007-83-4
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