IRF-1 Antibody / Interferon Regulatory Factor 1
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P10914
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 74-102 from the human protein was used as the immunogen for this IRF-1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IRF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IRF-1 antibody is available for research use only.
Storage Conditions
Aliquot the IRF-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IRF-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Bovine, Pig
Image Legend
IRF-1 antibody western blot analysis in human MDA-MB-231 cell lysate. Expected molecular weight: ~37 kDa (unmodified), 45-50 kDa (modified) .
Frequently Asked Questions
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