SOCS4 Antibody
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
Product Specifications
UniProt
Q8WXH5
Host
Rabbit
Immunogen
A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, IF, WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOCS4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOCS4 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/6679352/datasheet/f41736-0.4ml.pdf
CAS Number
9007-83-4
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