RHEB Antibody
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q15382
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 104-134 from the human protein was used as the immunogen for this RHEB antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RHEB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RHEB antibody is available for research use only.
Storage Conditions
Aliquot the RHEB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the RHEB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Bovine
Image Legend
RHEB antibody immunohsitochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle.
Documents
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