CREB Antibody
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
P16220
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 105-132 from the human protein was used as the immunogen for this CREB antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IF, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CREB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CREB antibody is available for research use only.
Storage Conditions
Aliquot the CREB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CREB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat, Bovine
Image Legend
CREB antibody western blot analysis in HT29 lysate. Predicted molecular weight is 37 kDa but routinely observed at ~43 kDa.
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