MSH2 Antibody
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P43246
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 637-665 from the human protein was used as the immunogen for this MSH2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, FACS, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MSH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MSH2 antibody is available for research use only.
Storage Conditions
Aliquot the MSH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MSH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
MSH2 antibody western blot analysis in SW480 lysate.
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