TdT Antibody / DNA nucleotidylexotransferase
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P04053
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 438-467 from human DNA nucleotidylexotransferase was used as the immunogen for this TdT antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TdT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TdT antibody is available for research use only.
Storage Conditions
Aliquot the TdT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TdT antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
TdT antibody western blot analysis in K562 lysate. Predicted molecular weight ~55 kDa
Documents
Frequently Asked Questions
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