MITF Antibody
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
O75030
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-28 from the human protein was used as the immunogen for this MITF antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MITF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MITF antibody is available for research use only.
Storage Conditions
Aliquot the MITF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MITF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
Western blot testing of MITF antibody at 1:2000 dilution + A375 lysate; Predicted molecular weight: 55-60 kDa.
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