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HNF1B Antibody

This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P35680

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 498-529 from the human protein was used as the immunogen for this HNF1B antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the HNF1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HNF1B antibody is available for research use only.

Storage Conditions

Aliquot the HNF1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the HNF1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat

Image Legend

HNF1B antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~ 61 kDa.

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