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ICAM2 Antibody

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Flow Cytometry: 1:10-1:50

UniProt

P13598

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 191-218 from the human protein was used as the immunogen for this ICAM2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the ICAM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ICAM2 antibody is available for research use only.

Storage Conditions

Aliquot the ICAM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ICAM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

ICAM2 antibody western blot analysis in HepG2 lysate. Expected molecular weight: 31-60 kDa depending on glycosylation level.

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