CB2 Antibody / Cannabinoid Receptor 2
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Cannabinoid receptor 2 and cannabinoid receptor 1 (brain) (CNR1) have the characteristics of a guanine nucleotide-binding protein (G-protein) -coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P34972
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 329-356 from the human protein was used as the immunogen for this CB2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, FACS, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CB2 antibody is available for research use only.
Storage Conditions
Aliquot the CB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CB2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma.
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