ABCC3 Antibody
Canalicular multispecific organic anion transporter 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
O15438
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 899-925 from the human protein was used as the immunogen for this ABCC3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, FACS, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ABCC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ABCC3 antibody is available for research use only.
Storage Conditions
Aliquot the ABCC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ABCC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, membranous
Image Legend
ABCC3 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma.
Frequently Asked Questions
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