Eph Receptor B2 Antibody [EPHB2]
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50, IHC (Paraffin) : 1:200
UniProt
P29323
Host
Mouse
Reactivity
Human
Immunogen
Purified His-tagged protein (from amino acids 127~425) was used to produce this monoclonal EPHB2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
48CT12.6.4
Applications
FACS, IHC, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the EPHB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This EPHB2 antibody is available for research use only.
Storage Conditions
Aliquot the EPHB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the EPHB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis partial EPHB2 protein using EphB2 antibody at 1:1000.
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