SOD2 Antibody

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:2000, IHC (Paraffin) : 1:10-1:50

UniProt

P04179

Host

Mouse

Reactivity

Human

Immunogen

Purified His-tagged protein fragment was used to produced this monoclonal SOD antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

37CT127.5.11.6

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the SOD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SOD2 antibody is available for research use only.

Storage Conditions

Aliquot the SOD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the SOD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of SOD2 antibody at 1:2000 dilution and human samples. Lane 1: HeLa lysate; 2: brain; 3: heart; 4: liver lysate; Predicted molecular weight ~ 25 kDa.