LRRK2 Antibody
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:500
UniProt
Q5S007
Host
Mouse
Reactivity
Human, Mouse
Immunogen
This LRRK2 antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.
Clonality
Monoclonal
Isotype
IgG1
Clone
133AT720
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the LRRK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This LRRK2 antibody is available for research use only.
Storage Conditions
Aliquot the LRRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
The LRRK2 antibody used in western blot to detect LRRK2/PARK8 in mouse brain cell lysate.
Documents
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