KLF4 Antibody
KLF4 is a transcription factor that can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:2000, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
O43474
Host
Mouse
Reactivity
Human
Immunogen
Recombinant protein was used to produce this monoclonal KLF4 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
56CT5.1.6
Applications
WB, IF, FACS, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KLF4 antibody is available for research use only.
Storage Conditions
Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/klf4-antibody-56ct516-f40406
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
