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ADA Antibody

This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100-1:250

UniProt

P00813

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 287-314 from the human protein was used as the immunogen for this ADA antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

608CT2.1.3

Applications

WB, ELISA

Purity

Protein G affinity

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ADA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ADA antibody is available for research use only.

Storage Conditions

Aliquot the ADA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

ADA antibody western blot analysis in (1) CEM and (2) Jurkat lysate. Expected/observed molecular weight ~41 kDa.

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