ADA Antibody
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:250
UniProt
P00813
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 287-314 from the human protein was used as the immunogen for this ADA antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
608CT2.1.3
Applications
WB, ELISA
Purity
Protein G affinity
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ADA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ADA antibody is available for research use only.
Storage Conditions
Aliquot the ADA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ADA antibody western blot analysis in (1) CEM and (2) Jurkat lysate. Expected/observed molecular weight ~41 kDa.
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