MUC1 Antibody
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].
Product Specifications
Specifications
Western blot: 1:100-1:250
UniProt
P15941
Host
Mouse
Reactivity
Human
Immunogen
Purified His-tagged N-terminal protein fragment was used to produced this monoclonal MUC1 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
347CT26.1.3
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MUC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MUC1 antibody is available for research use only.
Storage Conditions
Aliquot the MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/muc1-antibody-347ct2613-f40337
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
CAS Number
9007-83-4
Image Legend
MUC1 antibody western blot analysis in MDA-MB435 lysate. This Ab will detect the 23-29 kDa isoforms of MUC1.
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