PDK4 Antibody
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:100
UniProt
Q16654
Host
Mouse
Reactivity
Human
Immunogen
A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
345CT19.6.2
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PDK4 antibody is available for research use only.
Storage Conditions
Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
PDK4 antibody western blot analysis in K562 lysate. Expected/observed molecular weight ~46 kDa.
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