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PDK4 Antibody

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:100

UniProt

Q16654

Host

Mouse

Reactivity

Human

Immunogen

A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.

Clonality

Monoclonal

Isotype

IgG1

Clone

345CT19.6.2

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PDK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PDK4 antibody is available for research use only.

Storage Conditions

Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

PDK4 antibody western blot analysis in K562 lysate. Expected/observed molecular weight ~46 kDa.

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